A ribbon diagram of allophycocyanin, with the phycocyanobilin chromophores in a space-filling representation, is superimposed on photomicrograph images of two cyanobacteria, Spirulina and Oscillatoria. An experiment that examines the folding of phycobiliproteins is described in the article "Structural Studies of Phycobiliproteins from Spirulina: Combining Spectroscopy, Thermodynamics, and Molecular Modeling in an Undergraduate Biochemistry Experiment" by Ann T. S. Taylor and Scott E. Feller. The photomicrograph used to create the background composite image is courtesy of Michael W. Clayton, Department of Botany, University of WisconsinMadison.

The cover was designed by Betsy True.
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