Using Physical Models of Biomolecular Structures To Teach Concepts of Biochemical Structure and Structure Depiction in the Introductory Chemistry Laboratory
Gordon A. Bain, John Yi, and Mithra Beikmohamadi
Department of Chemistry, University of Wisconsin–Madison, Madison, WI 53706
Timothy M. Herman and Michael A. Patrick
Center for BioMolecular Modeling, Milwaukee School of Engineering, Milwaukee, WI 53202-3109
Basic concepts of biomolecular structure were introduced to students in the laboratory portion of a large-enrollment first-year chemistry class. Custom-made physical models of α-helices and β-sheets, the zinc finger moiety, β-globin, and green fluorescent protein were used. α-Helix and DNA construction kits were also employed. Students investigated primary, secondary, and tertiary structure of proteins.
Supplement
Instructions for the students, notes for the instructor, a guide for the teaching assistants, and the preparatory tutorials are available.
Contents
Folder JCE2006p1322W containing JCE2006p1322W_1.doc and JCE2006p1322W_2.doc (Microsoft Word) and JCE2006p1322W_1.pmd and JCE2006p1322W_2.pmd (PageMaker).
Bain, Gordon A.; Yi, John; Beikmohamadi, Mithra; Herman, Timothy M.; Patrick, Michael A. J. Chem. Educ.2006 83 1322.
Keywords
Amino Acids; Biochemistry; First-Year Undergraduate / General; Hands-On Learning / Manipulatives; High School / Introductory Chemistry; Laboratory Instruction; Molecular Modeling; Nucleic Acids / DNA / RNA; Proteins / Peptides
History
Created:
Last Updated:
8/7/2006
8/14/2006
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