TOPIC: 4

TOPIC: 4. Stereochemistry

SUBTOPIC: 40. Stereoisomers

1. Which compound that has the R configuration?

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2. Consider the following compounds in Fischer projection.

Which are meso compounds? Which are enantiomers? Which are diastereomers?

Which are achiral?

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3. Draw meso 2,3-dichlorobutane in its most stable conformation using the wedge and dash 3-D structure.

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4. For each of the following pairs of structures identify them as conformational isomers, enantiomers, diastereomers, structural isomers or identical.

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5. Rank the following substituents in order of priority according to the CIP Rules. Highest priority is 1.

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6. Identify the following as structural isomers, conformational isomers, enantiomers, diastereomers or identical.

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7. Name the following alkane.

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8. Identify the following as structural isomers, conformational isomers, enantiomers, diastereomers or identical.

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9. Give the R or S designation of the stereogenic center of each compound.

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10. Give the R or S designation of the stereogenic center of each compound.

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