5087

Suggest a synthetic sequence for each of the following transformations.

(a)

(b)

5168

Synthesize the following compounds starting from benzene and any other reagents of your choice. Each synthesis may include several steps. Duplicate synthesis of the same species is not necessary.

(a)

(b)

(c)

(d)

5259

Suggest a method for the synthesis of the following compounds starting from benzene unless otherwise specified, and using other simple reagents as necessary. Comment on critical reaction features, including the need to separate isomers when necessary.

(a)

(b)

(c)

(d)