TOPIC: 19. Carboxylic Acids

SUBTOPIC: 193. Amides

1. Which of the following compounds is easiest to hydrolyze? Which one is most difficult to hydrolyze?

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2. Give the major product(s) of the following reaction.

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3. Give a specific example of the hydrolysis of an amide. Write an equation showing starting material, reagents and products.

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4. Show the reagents necessary for the following transformation. Number the steps required if the reagents cannot be mixed at the same time. Mark each as an Oxidation, Reduction or Neither.

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5. Show the reagents necessary for the following transformation. Number the steps required if the reagents cannot be mixed at the same time. Mark each as an Oxidation, Reduction or Neither.

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6. Write the reagents over the arrow. Number them if they cannot be mixed.

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7. Give the major product(s) of the following reaction.

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8. Write the reagents over the arrow. Number them if they cannot be mixed.

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9. Write the mechanism of the following reaction. Show all intermediates and electron-pushing arrows.

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10. Show how you would accomplish the following synthesis. Show all reagents over the arrow and isolated compounds along the way.

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