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  Home > JCE Print > Journal of Chemical Education > Issues > 1995  > August  >
Symposium: Sweeteners and Sweetness Theory
Using Models to Understand and Design Sweeteners
D. Eric Walters
Department of Biological Chemistry, Finch University of Health Sciences, The Chicago Medical School, North Chicago, IL 60064
Cover
August 1995
Vol. 72 No. 8
p. 680
Abstract
While most sweeteners have been discovered accidentally, many models have been devised to aid in understanding structure-taste relationships. Because of the diversity of structures which may exhibit sweet taste, it is difficult to devise a comprehensive model. In fact, it may not be appropriate to fit all sweeteners into a single model since multiple receptors may be involved. This paper describes the evolution of sweetness receptor models, culminating in computer-derived models which have successfully been used in the design of new sweeteners and in predicting how sweet new analogs will be.
More Information
*  Citation
 Walters, D. Eric. J. Chem. Educ. 1995 72 680.
*  Keywords
*  History
 Created:
Last Updated:		 10/1/1999
5/22/2006
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