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  Home > JCE Print > Journal of Chemical Education > Issues > 1996  > December  >
In the Laboratory
Use of Infrared Spectroscopy in Monitoring a New Method for the Preparation of Sulotroban, an Antithrombotic Drug: A Medicinal Chemistry Experiment
Alain Nuhrich, Martine Varache-Lembège, Fabrice Martin, and Guy Devaux,
Laboratoire de Pharmacie Chimique et Chimie Therapeutique. Universite Victor Segalen. (Bordeaux II) 3, Place de la Victoire, 33076 Bordeaux Cedex - France
Cover
December 1996
Vol. 73 No. 12
p. 1185
Abstract
The authors propose an example of medicinal chemistry experiment that is concerned by future chemists, particularly, advanced students in universities. A new synthetic approach to Sulotroban, an antithrombotic drug is described. The chemical experimental procedures given integrate an infrared spectroscopy technique for monitoring the chromatographic purification processes used in this synthesis. The purpose of the proposed manipulations is to reflect in a concrete manner the reality of doing research on and preparing drugs of chemical origin.
More Information
*  Citation
 Nuhrich, Alain; Varache-Lembège, Martine; Lacan, Fabrice; Devaux, Guy. J. Chem. Educ. 1996 73 1185.
*  Keywords
 Laboratory Instruction
*  History
 Created:
Last Updated:		 August 5, 1999
February 21, 2006
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