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  Home > JCE Print > Journal of Chemical Education > Issues > 1997  > March  >
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Three Programs for DOS: Abstract of Volume 10B, Number 1 1. DNA Sequencing
John F. Beck and David L. Bunbury
Deparment of Chemistry, St. Francis Zavier University, Antigonish, N. S. B2G 1C0, Canada

Cover
March 1997
Vol. 74 No. 3
p. 346

Full Text
DNA Sequencing is a package of five programs that instructs and tests students on the Maxam-Gilbert method of sequencing DNA. It can be used as a self-instruction unit, as an assignment, and as a testing vehicle. The package is aimed at a university level chemistry, biochemistry, or chemical-biology course, but advanced senior high school students will also find it useful. The central feature of the package randomly generates a nucleic acid fragment and simulates the subsequent Maxam-Gilbert autoradiogram. Students are then guided through the method of interpreting the autoradiogram. Students require a prior, general knowledge of the DNA base structures and of the principles of electrophoresis. Knowledge of the chemistry of the cleavage reactions used in the method is helpful but not necessary to use these programs.

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*  Citation
Beck, John F.; Bunbury, David L. J. Chem. Educ. 1997 74 346.
*  Keywords
*  History
Created:
Last Updated:
July 29, 1999
June 23, 2005
  Home > JCE Print > Journal of Chemical Education > Issues > 1997  > March


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