Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry. Instrumentation and Applications
David C. Muddiman, Ray Bakhtiar, Steven A. Hofstadler, and Richard D. Smith Virginia Commonwealth University, Department of Chemistry, 1001 West Main Street, Richmond, VA 23284-2006
This article introduces educators and researchers to the theory, principles, instrumentation, and some applications of MALDI-MS. Reflectron time-of-flight (TOF) mass analyzers are described in detail, since TOF is the most common mass analyzer for ions produced by MALDI. Several excellent reviews give a more detailed account of MALDI-MS.
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