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  Home > JCE Print > Journal of Chemical Education > Issues > 1997  > June  >
Symposium: Applications of Inorganic Photochemistry
Perfect Strangers: Inorganic Photochemistry and Nucleic Acids
Pamela J. Carter, Suzanne A. Ciftan, Mark F. Sistare, and H. Holden Thorp
Department of Chemistry, University of North Carolina, Chapel Hill, NC 27599-3290
Cover
June 1997
Vol. 74 No. 6
p. 641
Abstract
The applications of inorganic photochemistry to nucleic acid chemistry are discussed. A brief review of nucleic acid structure is given. Methods for probing DNA using emissive inorganic complexes are discussed. Photoreactions that damage DNA by hydrogen atom transfer from sugar or electron abstraction from guanine are presented. The method of photochemical footprinting using a diplatinum photocatalyst is described. The final section discusses advances in combinatorial selection experiments that increase the urgency for rapid screening methods such as those derived from inorganic photochemistry.
More Information
*  Citation
 Carter, Pamela J.; Ciftan Suzanne A.; Sistare, Mark F.; Thorp, H. Holden. J. Chem. Educ. 1997 74 641.
*  Keywords
 Biochemistry, Inorganic Chemistry, Drugs/Pharmaceuticals, Excited States/Energy Transfer, Photochemistry, Nucleic Acids
*  History
 Created:
Last Updated:		 July 28, 1999
June 23, 2005
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