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  Home > JCE Print > Journal of Chemical Education > Issues > 2000  > March  >
In the Laboratory
Experiments with Aspirin
Londa L. Borer
Department of Chemistry, California State University, Sacramento, Sacramento, CA 95819

Edward Barry
El Camino High School, Sacramento, CA 95821

Cover
March 2000
Vol. 77 No. 3
p. 354

Abstract
A series of experiments based on aspirin have been used in our high school chemistry laboratory. Experiments include (i) synthesis, purification, and characterization of aspirin by mp and TLC, (ii) percentage composition of a commercial aspirin tablet by titration, (iii) kinetics of the hydrolysis of aspirin to salicylic acid under various conditions, (iv) synthesis and characterization of copper(II) aspirinate and copper(II) salicylate, and (v) reaction of copper(II) aspirinate in aqueous solution.
Supplement
Synthetic and analytical procedures, Kinetics of Hydrolysis of ASA, Determination of the Effect of pH on the Formation of an Iron-Salicyclic Acid Complex, the Synthesis of Copper (II) Aspirinate and Salicylate, and references are included.
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More Information
*  Citation
Borer, Londa L.; Barry, Edward. J. Chem. Educ. 2000 77 354.
*  Keywords
Introductory / High School Chemistry; Organic Chemistry; Synthesis; Kinetics
*  History
Created:
Last Updated:
February 14, 2000
August 31, 2005
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