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  Home > JCE Print > Journal of Chemical Education > Issues > 2001  > October  >
In the Laboratory
Tablet Analysis Using Gravimetric Dilutions
Larry A. Simonson
Department of Chemistry and Food Science, Framingham State College, Framingham, MA 01701-9101

Cover
October 2001
Vol. 78 No. 10
p. 1387

Abstract

This experiment introduces the concept of gravimetric dilutions in the context of tablet analysis. Caffeine tablets are analyzed by absorbance at 274 nm with reference to a standard calibration graph and tested for compliance with the USP criterion. All samples and standards are prepared using gravimetric dilutions without reference to volume or density. This experiment is appropriate for high school and college freshman chemistry courses and may be useful at higher levels. It is only necessary that students have had exposure to Beer's law.

Supplement
A handout containing detailed instructions for students is available.
*  Contents JCE2001p1387W.doc (Microsoft Word)
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More Information
*  Citation
Simonson, Larry A. J. Chem. Educ. 2001 78 1387.
*  Keywords
Analytical Chemistry; Drugs / Pharmaceuticals; Laboratory Instruction; Quantitative Analysis; UV-Vis Spectroscopy
*  History
Created:
Last Updated:
September 13, 2001
August 31, 2005
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