Over the past decade the chemical, and in particular the pharmaceutical industry, has experienced a tremendous push toward miniaturization. No longer are we content to carry out chemistries in test tubes or 96-well microtiter plates, but are now utilizing 384-well plates and looking towards 1536 high-density formats, which occupy the same footprint area as a 96-well plate. So called lab-on-a-chip systems are taking the technology one step further--they allow integration of several components into the micro world, to an extent that has not been possible before. Based on the author's work in the pharmaceutical research and development industry, this article focuses on the application of lab-on-a-chip in chemical synthesis and analysis, explores some of its possibilities, and cites some work in the field. The content is targeted to university educators, primarily, and students.
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