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2003
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Chemical Education Today
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NSF Highlights
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An NMR-Smell Module for the First-Semester General Chemistry Laboratory
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Erich S. Uffelman, Elizabeth H. Cox, and J. Brown Goehring
Department of Chemistry, Washington and Lee University, Lexington, VA 24450
Tyler S. Lorig
Department of Neuroscience, Washington and Lee University, Lexington, VA 24450
C. Michele Davis
Department of Chemistry, Georgia Southern University, Statesboro, GA 30460
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December 2003
Vol. 80 No. 12
p. 1368
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| Abstract |
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This article describes a module of NMR-smell experiments for the general chemistry laboratory that can be taught in two-week or three-week formats; the module has also been run in a modified form with high school students during the summer. The series of experiments involves an exploration of organic stereochemistry via hands-on model building, several chemosensory smell tests, and hands-on use of 13C NMR, thus serving as a powerful interdisciplinary lab involving chemistry, physics, and neuroscience. Similarities and differences between NMR and MRI methods are emphasized. By the end of the NMR-smell module, students have a very basic knowledge of the physics of the NMR process, the ability to identify different types of organic isomerism, the ability to identify stereogenic centers in molecules, and a basic knowledge of the importance of 3-D structure in chemistry. The less quantifiable, but in some ways more important, benefits of the module that students really appreciate are getting to "touch and play" with the NMR, running the smell tests and seeing the strengths and limitations of their noses as analytical instruments, and seeing how the basic chemistry and physics of NMR relate to MRI.
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| Supplement |
Instructor notes, detailed procedures for the laboratory, and student handouts are available.
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 Contents |
JCE2003p1368W.doc (Microsoft Word)
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| More Information |
Citation |
Uffelman, Erich S.; Cox, Elizabeth H.; Goehring, J. Brown; Lorig, Tyler S.; Davis, C. Michele. J. Chem. Educ. 2003 80 1368.
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Keywords |
General Chemistry; Laboratory Instruction; NMR Spectrometry; Stereochemistry
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History |
Created:
Last Updated: |
October 31, 2003
February 28, 2005
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| Home > JCE Print > Journal of Chemical Education > Issues >
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