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  Home > JCE Print > Journal of Chemical Education > Issues > 2003  > February  >
Chemical Education Today
Report: Nobel Prize in Chemistry, 2002
Using Mass Spectrometry for Proteins
Martha M. Vestling
Department of Chemistry Instrumentation Center, University of Wisconsin-Madison, Madison, WI 53706
Cover
February 2003
Vol. 80 No. 2
p. 122
Abstract
The 2002 Chemistry Nobel Prize has mass spectrometrists everywhere celebrating. It recognizes work that put large proteins, 10,000 Da and up, into mass spectrometers. A description of Koichi Tanaka's experiments using laser desorption ionization and John B. Fenn's experiments using electrospray ionization is given along with a brief summary with references to previous researchers' work that Tanaka and Fenn were familiar with. The techniques Tanaka and Fenn used for their Prize-winning work—techniques that have revolutionized mass spectrometry—have yet to reach current chemistry textbooks, whatever their level.
More Information
*  Citation
 Vestling, Martha M. J. Chem. Educ. 2003 80 122.
*  Keywords
 Electrospray*; History / Philosophy; Instrumental Methods; Ionization*; Laboratory Equipment / Apparatus; Laser Desorption*; MALDI*; Mass Spectrometry; Mass Spectrometry; Nobel Prize*; Proteins / Peptides
*  History
 Created:
Last Updated:		 January 6, 2003
February 28, 2005
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