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  Home > JCE Print > Journal of Chemical Education > Issues > 2004  > January  >
In the Classroom
From Metalloproteins to Coordination Chemistry: A Learning Exercise To Teach Transition Metal Chemistry
John Reglinski, Duncan Graham, Alan R. Kennedy, and Lorraine T. Gibson
Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow G1 1XL, United Kingdom
Cover
January 2004
Vol. 81 No. 1
p. 76
Abstract
This paper presents an exercise in inorganic chemistry that examines the principles of coordination chemistry, ligand design, and catalysis by looking at the breadth of chemistry displayed by metalloproteins. This exercise offers an alternative perspective on coordination chemistry by developing the topic in reverse—from use to design. Students obtain visually stunning images from the protein crystallographic database and analyze the metal environments of these species in relation to the X-ray crystal structures of simple inorganic complexes and data on the chemistry of these model complexes through the use of electronic libraries. By offering the students a highly visual, reversed perspective on coordination chemistry, we have circumvented many of the minor intellectual hurdles that make this subject frustrating for the beginner. For students with an aptitude in this area, the exercise offers an opportunity for them to apply their knowledge of inorganic chemistry and develop lateral thought processes involving previously learned material.
More Information
*  Citation
 Reglinski, John; Graham, Duncan; Kennedy, Alan R.; Gibson, Lorraine T. J. Chem. Educ. 2004 81 76.
*  Keywords
 Bioinorganic Chemistry; CER Problem Solving; CER Student-Centered Learning; Computer Assisted Instruction; Inorganic Chemistry; Proteins / Peptides; Teaching / Learning Aids; Transition Elements
*  History
 Created:
Last Updated:		 December 8, 2003
February 18, 2005
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