|
|
| Home > JCE Print > Journal of Chemical Education > Issues >
2004
>
July
> |
|
Chemical Education Today
|
|
Report
|
|
The Nobel Prize in Medicine for Magnetic Resonance Imaging
|
Charles G. Fry
Department of Chemistry, University of Wisconsin–Madison, Madison, WI 53706
|
|
July 2004
Vol. 81 No. 7
p. 922
|
|
|
|
|
|
|
| Abstract |
|
A review is given of the crucial work performed by Paul C. Lauterbur and Peter Mansfield that lead to their being awarded the Nobel Prize in Medicine in 2003. Lauterbur first expounded the idea of mapping spatial information from spectral data in nuclear magnetic resonance (NMR) through the application of magnetic field gradients (P. C. Lauterbur, Nature 1973, 242, 190-191). One year later Mansfield and co-workers introduced the idea of selective excitation to NMR imaging (A. N. Garroway, P. K. Grannell, and P. Mansfield. J. Phys. C: Solid State Physics 1974, 7, L457-L462). A major step in making the technique useful for clinical imaging came with Mansfield's publication of the method known as echo planar imaging (P. Mansfield, J. Phys. C: Solid State Physics 1977, 10 (3), L55-L58). Lauterbur's and Mansfield's work captured the essence of scientific discovery, collaboration, and concerted effort to overcome significant technical issues, and were key to the development of the technique of magnetic resonance imaging (MRI). Examples of how MRI technology can be extended to chemical research are given, and limitations of the technique in this regard are discussed. Discussion of how to use commonly available NMR spectrometers for chemical imaging is also provided.
|
|
| More Information |
 Citation |
Fry, Charles G. J. Chem. Educ. 2004 81 922.
|
Keywords |
History / Philosophy; Medicinal Chemistry; NMR Spectrometry
|
History |
Created:
Last Updated: |
May 27, 2004
January 19, 2005
|
|
|
|
|
|
| Home > JCE Print > Journal of Chemical Education > Issues >
2004
>
July
> Page
922
|
|
|
| JCE HS CLIC |
|
Our Secondary School editors work hard to distill all the JCE materials to produce a fraction of particular interest to high school teachers. We call it CLIC.
|
| Contributions Welcome |
| JCE welcomes your submission |
| Advertisers |
| In recent years we have worked hard to better match our advertisers with our readers. When shopping for chemistry education materials, visit our advertisers' WWW sites first. |
| Be An Ambassador |
| Take JCE along on your outreach missions. Copies of the Journal, guest access to JCE Online, our publications catalog, and more are available for your participants. |
|
