There is no question that the field of analytical chemistry has had a profound beneficial effect on society during the 19th and 20th centuries. The painstaking and often painfully frustrating work by analytical chemists is the stuff of which Nobel Prizes are made. Nonetheless, the engineering community must often remind these highly dedicated researchers that the original invention is frequently only the tip of the iceberg on the road from origin to commercialization. This article traces the history of the engineering development related to the several generations of ion chromatography instruments, columns, suppressers, and software. In so doing, several representative engineering challenges and their outcomes are discussed including: early directions (traveling without a road map, or "going where the applications are"), dealing with an extremely corrosive mobile phase (aka: the "eluent"), resolving the inherent incompatibilities of nonmetallic flow paths with the benefits of high-pressure, elevated temperature operation, managing the ever-evolving nature of the suppressor, coping with requirements for ultra high-end online systems, and providing extremely simple-to-use dedicated analyzer systems. Of particular note are stories of "reinventing for the first time" practices common to HPLC at that time but for which there was little or no experience with respect to challenges unique to ion chromatography.
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Citation
Evans, Barton. J. Chem. Educ.2004 81 1285.
Keywords
Analytical Chemistry; Chromatography; History / Philosophy; Industrial Chemistry; Instrumental Methods; Ion Exchange; Laboratory Equipment / Apparatus; Separation Science; Water / Water Chemistry
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