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2005
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In the Laboratory
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Decomposition of Aspartame. A Kinetics Experiment for Upper-Level Chemistry Laboratories
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Kathryn R. Williams, Bhavin Adhyaru, Julia Timofeev, and Michael Keith Blankenship
Department of Chemistry, University of Florida, Gainesville, FL 32611-7200
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June 2005
Vol. 82 No. 6
p. 924
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| Abstract |
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In this experiment, students study the kinetics of decomposition of aspartame for three reaction conditions: 0.20 M citrate, pH 7.0, 40 °C; 0.20 M phosphate, pH 7.0, 40 °C; 0.20 M phosphate, pH 7.0, 55 °C. They calculate the activation energy and observe the large rate enhancement in phosphate compared to citrate, due to the bifunctional nature of the HPO42− anion. The only major instrumentation requirement is an HPLC with a variable-wavelength UV detector. The experiment can be completed in one five-hour laboratory period.
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| Supplement |
Instructions for the students (including a prelab exercise) and notes for the instructor are available.
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 Contents |
JCE2005p0924W.doc (Microsoft Word)
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| Download |
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| More Information |
Citation |
Williams, Kathryn R.; Adhyaru, Bhavin; Timofeev, Julia; Blankenship, Michael Keith. J. Chem. Educ. 2005 82 924.
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Keywords |
Biochemistry; Biophysical Chemistry; Consumer Chemistry; Food Science; Hands-On Learning / Manipulatives; HPLC; Kinetics; Laboratory Instruction; Physical Chemistry; Proteins / Peptides; Upper-Division Undergraduate
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History |
Created:
Last Updated: |
April 27, 2005
May 11, 2005
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| Home > JCE Print > Journal of Chemical Education > Issues >
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924
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