JCE Online Journal of Chemical EducationDivision of Chemical Education, American Chemical SocietyAmerican Chemical Society
 | Subscriptions  | Software Orders  | Support  | Contributors  | Advertisers  | 

JCE Print
   Current Issue
 Previous Issues
 Supplements
 Search JCE Index

JCE Digital Library
   ChemInfo
 DigiDemos
 Featured Molecules
 LivTexts
 LrnCom
 QBank
 SymMath
 WebWare

JCE Software
   Latest Releases
 Software & Video
 Downloads
 Support

Only@JCE Online
   JCE Online Store
 JCE HS CLIC
 JCE Discussion Forums
   Biographical Snapshots
 ChemEd Resource Shelf
 Featured Molecules
 Hal's Picks
 Project Chemlab
 Reviewed WWW Sites
 "Web-Ed" Articles

About JCE
   Features
 Publications
 Operations
 Outreach
 Contact Us


  Home > JCE Print > Journal of Chemical Education > Issues > 2006  > December  >
Chemistry for Everyone
Products of Chemistry
Nature's Way To Make the Lantibiotics
Heather A. Relyea and Wilfred A. van der Donk
Department of Chemistry, University of Illinois, Urbana, IL 61801
Cover
December 2006
Vol. 83 No. 12
p. 1769
Abstract
Antibiotic resistance poses a serious threat for human health. Renewed effort towards discovery of new antibiotics is essential to ward off a widespread return of lethal infectious diseases to the developed world and to continue combating infectious diseases in the developing world. Traditionally, chemical education focuses on synthetic chemical means of producing pharmaceuticals. However, with the enormous advances in molecular biology techniques in the 1980s and genome sequence information in the 1990s, the use of nature's synthetic tools is on the rise as an important alternative avenue for production of drugs. This article focuses on one class of antimicrobial compounds, the lantibiotics, and discusses their biosynthetic pathways as well as their molecular mode of action. In the course of the review, the meaning of the terms regio-, chemo-, and stereoselectivity are discussed.
More Information
*
Citation
Relyea, Heather A.; van der Donk, Wilfred A. J. Chem. Educ. 2006 83 1769.
*
Keywords
Applications of Chemistry; Biochemistry; Bioorganic Chemistry; Biosynthesis; Biotechnology; Catalysis; Drugs / Pharmaceuticals; First-Year Undergraduate / General; High School / Introductory Chemistry; Organic Chemistry; Proteins / Peptides; Second-Year Undergraduate; Textbooks / Reference Books
*
History
Created:
Last Updated:
10/30/2006
10/31/2006
<< Previous Article Table of Contents Next Article >>
  Home > JCE Print > Journal of Chemical Education > Issues > 2006  > December  > Page 1769


Subscriptions
 Subscription Info
 Order Forms

JCE HS CLIC

Our Secondary School editors work hard to distill all the JCE materials to produce a fraction of particular interest to high school teachers. We call it CLIC.
 JCE HS CLIC

Contributions Welcome
JCE welcomes your submission
 Contributors' Corner

Advertisers
In recent years we have worked hard to better match our advertisers with our readers. When shopping for chemistry education materials, visit our advertisers' WWW sites first.
 Recent Advertisers

Be An Ambassador
Take JCE along on your outreach missions. Copies of the Journal, guest access to JCE Online, our publications catalog, and more are available for your participants.
 Outreach with JCE

Comments to
jceonline@chem.wisc.edu		 Copyright © Division of Chemical Education, Inc., American Chemical Society.
All rights reserved.