The cover features two views of glass-ionomer cement, a modern dental filling material. A transmission electron micrograph displays a cross- section through a set glass-ionomer cement and a photograph shows a molar restored with this material. The article "Chemistry of Modern Dental Filling Materials" by John W. Nicholson and H. Mary Anstice appears on pages 1497-1501. The transmission electron micrograph is used with the permission of Paul Hatton and Ian Brook, University of Sheffield, UK.

The cover was designed by Betsy True.
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