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  Home > JCE Print > Journal of Chemical Education > Issues > 2000  > March  >
Information, Textbooks, Media, Resources
An Unexpected Event When Chymotrypsin Performs Its Physiological Role
Ivan G. Darvey
Department of Biochemistry, The University of Sydney, Sydney, NSW 2006, Australia
Cover
March 2000
Vol. 77 No. 3
p. 422
Abstract
One of the events that occur during the chymotrypsin-catalyzed hydrolysis of proteins is an example of an exception to a rule of thumb taught in introductory organic chemistry courses, namely, that amides can't readily be converted to esters. If biochemistry teachers and the authors of textbooks of biochemistry commented on this unusual reaction, it would emphasize further the remarkable part chymotrypsin plays as a catalyst in carrying out its main perceived "physiological role".
More Information
*  Citation
 Darvey, Ivan G. J. Chem. Educ. 2000 77 422.
*  Keywords
 Biochemistry; Catalysis; Enzymes; Organic Chemistry
*  History
 Created:
Last Updated:		 February 14, 2000
April 15, 2005
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