The Stereochemistry of Biochemical Molecules: A Subject to Revisit
Josep J. Centelles and Santiago Imperial
Departament de Bioquímica i Biologia Molecular, Facultat de Química, Universitat de Barcelona, 08028-Barcelona, Spain
Although Fischer’s convention for stereoisomers is useful for simple molecules, the stereochemistry of complex biochemical molecules is often poorly indicated in textbooks. This article reports on errors in stereochemistry of complex hydrosoluble vitamin B12 molecule. Twenty-five popular biochemistry textbooks were examined for their treatment of the stereoisomery of vitamin B12. Mistakes, discrepancies, and oddities reported in vitamin B12 are just an example of this problem. Biochemistry textbook authors and teachers should pay more attention to the stereoisomery of biochemical molecules to avoid students’ confusion.
More Information
Citation
Centelles, Josep J.; Imperial, Santiago. J. Chem. Educ.2005 82 75.
Our Secondary School editors work hard to distill all the JCE materials to produce a fraction of particular interest to high school teachers. We call it CLIC.
In recent years we have worked hard to better match our advertisers with our readers. When shopping for chemistry education materials, visit our advertisers' WWW sites first.
Take JCE along on your outreach missions. Copies of the Journal, guest access to JCE Online, our publications catalog, and more are available for your participants.