Electrospray Ionization Mass Spectrometry: Part II: Applications in Characterization of Peptides and Proteins
Ray Bakhtiar, Steven A. Hofstadler, and Richard D. Smith
Chemical Sciences Department and Environmental, Molecular Science Laboratory, Pacific Northwest National Laboratory, Richland, WA 99352
In part I of this article, we discussed the theory and operational features of electrospray ionization mass spectrometry (ESI-MS). Herein, we survey a few common applications of ESI-MS. The symbiotic relationship between biological chemists and mass spectrometrists has lead to rapid development of commercial ESI-MS systems and their utilization by an ever growing number of researchers. It is our hope in this article to answer the question: What do ESI-MS measurements tell researchers and how does this information assist their research?
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Citation
Bakhtiar, Ray; Hofstadler, Steven A.; Smith, Richard D. J. Chem. Educ.1996 73 A118.
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